Pycnogenol®, Arborvitae and Cognitive Health
Pycnogenol is the purest form of maritime pine bark extract available, and is the primary active ingredient in Arborvitae’s range of natural supplements
Cognitive Health – Research Abstract
Research shows Pycnogenol and its unique properties can help improve cognitive health at all ages.
A normal cognitive function is a prerequisite for a healthy life. The brain function may be altered in case of either hyperactivity or hypo-activity of the brain. Hyperactivity is frequently observed in children, commonly referred to as Attention Deficit Hyperactivity Disorder (ADHD), whereas the decline of brain activity is related to the aging process.
It is very remarkable that Pycnogenol, French maritime pine bark extract is able to both reduce hyperactivity in children and improve memory and cognitive function in adults.
Pycnogenol is able to regulate the endothelial function
The active metabolites of Pycnogenol build up inside the endothelial blood cells and have been proven to pass the blood-brain barrier (4). Pycnogenol helps endothelial cells produce more nitric oxide (NO) which has multiple effects on brain function. Initially, NO increases blood flow (1), which improves oxygenation and the transport of nutrients to brain cells. Furthermore, NO regulates neuronal functions and thus contributes to processing signals inside the brain (2). In addition, NO helps modulate key neurotransmitters such as dopamine, serotonin and norepinephrine (3).
Other cognitive health benefits covered in the report:
- Pycnogenol and Attention Deficit Hyperactivity Disorder
- Improvement of the cognitive function in adults, includes separate analysis of age groups from students to baby boomers
- Reduced oxidative stress
Source: Horphag Research